2012 | 2011 | All

Cadoo KA, McArdle O, O’Shea AM, Power CP, Hennessy BT. .
Management of unusual histologic subtypes of breast cancer.
Oncologist 2012 In Press.     PMID: NA      (Dec 2012)

Guiu S, Michiels S, André F, Cortes J, Denkert C, Di Leo A, Hennessy BT, Nielsen T, Sorlie T, Sotiriou C, Turner N, Van de Vijver M, Viale G, Loi S, Reis-Filho J. .
Molecular subclasses of breast cancer: How do we define them? The IMPAKT 2012 Working Group Statement.
Annalsof Oncology 2012 Dec;23(12):2997-3006     PMID: 23166150      (Dec 2012)

Mohd Sharial Z, Crown J, Hennessy BT. .
Overcoming Resistance and Restoring Sensitivity to HER2-Targeted Therapies in Breast Cancer.
Annals of Oncology 2012 Dec;23(12):3007-16     PMID: 22865781      (Dec 2012)

Timms KM, Abkevich V, Hennessy BT, Potter J, Carey MS, Meyer LA, Broaddus R, Lu KH, Jammulapati S, Fitzgerald L, Krivak T, DeLoia JA, Gutin A, Mills GB, Lanchbury JS. .
Patterns of Genomic Loss of Heterozygosity Predict Homologous Recombination Repair Defects in Epithelial Ovarian Cancer.
British J Cancer, 2012 Nov 6;107(10):1776-82     PMID: 23047548      (Nov 2012)

Kamel D, Brady B, Tabchy A, Mills GB, Hennessy BT. .
Proteomic Classification of Breast Cancer.
Current Drug Targets 2012 Nov 1;13(12):1495-509;     PMID: 22974393      (Nov 2012)

Liang H, Cheung LWT, Li J, Ju Z, Yu S, Stemke-Hale K, Dogruluk T, Lu Y, Liu X, Gu C, Guo W, Scherer SE, Carter H, Westin SN, Dyer MD, Verhaak RGW, Zhang F, Karchin R, Liu CG, Lu KH, Broaddus RR, Scott KL, Hennessy BT, Mills GB. .
Whole-exome Sequencing Combined with Functional Genomics Reveals Novel Candidate Driver Cancer Genes in Endometrial Cancer.
Genome Research 2012 Nov;22(11):2120-9     PMID: 23028188      (Nov 2012)

Guo H, Liu W, Ju Z, Tamboli P, Jonasch E, Mills GB, Lu Y, Hennessy BT, Tsavachidou D .
An Efficient Procedure for Protein Extraction from Formalin-fixed, Paraffin-embedded Tissues for Reverse Phase Protein Arrays.
Proteome Science Proteome Sci. 2012 Sep 24;10(1):56     PMID: 23006314      (Sep 2012)

Brady B, Kamel D, Kiely J, Hennessy BT. .
Dual Diagnosis of Sarcoidosis and Lymphoma.
Irish Journal of Medical Science 2012 Ir J Med Sci. 2012 Sep 17. [Epub ahead of print]     PMID: 22983882      (Sep 2012)

Oates CJ, Hennessy BT, Lu Y, Mills GB, Mukherjee S .
Network Inference using Steady-State Data and Goldbeter-Koshland Kinetics.
Bioinformatics 2012 2012 Sep 15;28(18):2342-8     PMID: 22815361      (Sep 2012)

Kim WY, Prudkin L, Feng L, Kim ES, Hennessy B, Lee JS, Lee JJ, Glisson B, Lippman SM, Wistuba II, Hong WK, Lee HY. .
Epidermal growth factor receptor and K-Ras mutations and resistance of lung cancer to insulin-like growth factor 1 receptor tyrosine kinase inhibitors.
Cancer 2012 Aug 15;118(16):3993-4003     PMID: 22359227      (Aug 2012)

Fu S, Hennessy BT, Ng CS, Ju Z, Coombes K, Wolf JK, Sood AK, Levenback CF, Coleman RL, Kavanagh JJ, Gershenson DM, Markman M, Dice K, Howard A, Li J, Li Y, Stemke-Hale K, Dyer M, Atkinson E, Jackson E, Kundra V, Kurzrock R, Bast Jr RC, Mills GB. .
Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer.
Gynecol Oncol, 126(1):47-53, 2012     PMID: 22487539      (Jul 2012)

Russell P, Hennessy BT, Li J, Carey MS, Bast RC, Freeman T, Venkitaraman AR. .
Cyclin G1 regulates the outcome of taxane-induced mitotic checkpoint arrest.
Oncogene 2012 May 10;31(19):2450-60     PMID: 22056875      (May 2012)

Djordjevic B, Hennessy BT, Li J, Barkoh BA, Luthra R, Mills GB, Broaddus RR. .
Clinical Assessment of PTEN Loss in Endometrial Carcinoma: Immunohistochemistry Out-Performs Gene Sequencing.
Modern Pathol 2012 May;25(5):699-708     PMID: 22301702      (May 2012)

Heiser LM, Sadanandam A, Kuo WL, Benz SC, Goldstein TC, Ng S, Gibb WJ, Wang NJ, Ziyad S, Tong F, Bayani N, Hu Z, Billig JI, Dueregger A, Lewis S, Jakkula L, Korkola JE, Durinck S, Pepin F, Guan Y, Purdom E, Neuvial P, Bengsston H, Wood KW, Smith PG, Vassilev L, Hennessy BT, Greshock JD, Bachman KE, Hardwicke MA, Park JW, Marton LJ, Wolf DM, Collisson EA, Neve RM, Mills GB, Speed TP, Feiler HS, Wooster RF, Haussler D, Stuart JM, Gray JW, Spellman PT. .
Subtype and pathway specific responses to anti cancer compounds in breast cancer.
Proc Natl Acad Sci U S A, 109(8):2724-2729, 2012.     PMID: 22003129      (Mar 2012)

Wang LE, Ma H, Hale KS, Yin M, Meyer LA, Liu H, Li J, Lu KH, Hennessy BT, Li X, Spitz MR, Wei Q, Mills GB. .
Roles of genetic variants in the PI3K and RAS/RAF pathways in susceptibility to endometrial cancer and clinical outcomes.
J Cancer Res Clin Oncol, 138(3):377-385, 2012     PMID: 22146979      (Mar 2012)

Pradeep CR, Köstler WJ, Lauriola M, Granit RZ, Zhang F, Jacob-Hirsch J, Rechavi G, Nair HB, Hennessy BT, Gonzalez-Angulo AM, Tekmal RR, Ben-Porath I, Mills GB, Domany E, Yarden Y. .
Modeling ductal carcinoma in situ: a HER2-Notch3 collaboration enables luminal filling.
Oncogene, 31(7):907-917, 2012     PMID: 21743488      (Feb 2012)

Park YY, Kim K, Kim SB, Hennessy BT, Kim SM, Park ES, Lim JY, Li J, Lu Y, Gonzalez-Angulo AM, Jeong W, Mills GB, Safe S, Lee JS. .
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer.
EMBO Mol Med, 4(1):52-67, 2012     PMID: 22174013      (Jan 2012)

Leonard R, Hennessy BT, Blum JL, O’Shaughnessy J. .
Dose-adjusting capecitabine minimizes adverse effects while maintaining efficacy: a retrospective review of capecitabine for metastatic breast cancer.
Clin Breast Cancer, 11(6):349-356, 2011.     PMID: NA      (Dec 2011)

Liang ZD, Long Y, Tsai WB, Fu S, Kurzrock R, Gagea-Iurascu M, Zhang F, Chen HW, Hennessy BT, Mills G, Savaraj N, Kuo MT. .
Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents.
Mol Cancer Ther 2012, Nov;11(11):2483-94     PMID: 22914438      (Nov 2011)

Gonzalez-Angulo AM (1st), Hennessy BT (1st), Meric-Bernstam F, Sahin A, Liu W, Ju Z, Carey MS, Myhre S, Speers C, Lei D, Broaddus R, Lluch AM, Aparicio S, Brown P, Pusztai L, Symmans WF, Alsner J, Overgaard J, Borresen-Dale AL, Hortobagyi GN, Coombes KR, Mills GB. .
Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.
Clin Proteomics, 8(1):11, 2011     PMID: PMC3170272      (Jul 2011)

Cheung LWT , Hennessy BT, Li J, Yu S, Myers AP, Djordjevic B, Lu Y, Stemke-Hale K, Zheng F, Ju Z, Cantley LC, Scherer SE, Liang H, Lu KH, Broaddus RR, Mills GB. .
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.
Cancer Discovery, 1(2):170-185, 2011     PMID: 21984976      (Jul 2011)

Stronach EA, Alfraidi AM, Rama NR, Datler C, Studd JB, Agarwal R, Guney TG, Gourley C, Hennessy BT, Mills GB, Mai A, Brown R, Dina R, Gabra H. .
HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer.
Cancer Res, 71(13):4412-4422, 2011.     PMID: 21571862      (Jul 2011)

Tabchy A, Hennessy BT, Gonzalez-Angulo AM, Bernstam FM, Lu Y, Mills GB. .
Quantitative Proteomic Analysis in Breast Cancer.
Drugs Today (Barc), 47(2):169-182, 2011     PMID: NA      (Jul 2011)

Kalachand R, Hennessy BT, Markman M. .
Molecular targeted therapy in ovarian cancer – what is on the horizon?
Drugs, 71(8):947-967, 2011     PMID: 21668036      (May 2011)

Wander SA, Hennessy BT, Slingerland JM. .
Next generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.
J Clin Invest, 121(4):1231-1241, 2011     PMID: 21490404      (Apr 2011)

Gonzalez-Angulo AM, Timms KM, Liu S, Chen H, Litton JK, Potter J, Lanchbury JS, Stemke-Hale K, Hennessy BT, Arun BK, Hortobagyi GN, Do KA, Mills GB, Meric-Bernstam F. .
Incidence and outcome of BRCA mutations in un triple receptor-negative breast cancer.
Clin Cancer Res, 17(5):1082-1089, 2011     PMID: 21233401      (Mar 2011)

Jotzu C, Alt E, Welte G, Li J, Hennessy BT, Devarajan E, Krishnappa S, Pinilla S, Droll L, Song YH. .
Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors.
Cell Oncol (Dordr), 34(1):55-67, 2011     PMID: 21327615      (Feb 2011)