Project Title Project Description Leading PI Co investigators Funding Source
Molecular Determinants of Seizure Induced Nueronal Death And Epileptogenesis.   Henshall David, RCSI - SFI Investigator Programme Grants
Characterization of PUMA as an essential promoter of seizure-induced cell death and its role in neuroprotection and epileptogenesis. Click here for Project Description Henshall David, RCSI - IRCSET Post-doctoral Fellowship
Mouse Monitoring Clinic for translational research   Henshall David, RCSI - HRB
Role of microRNAs in the molecular mechanism of neuroprotection by epileptic preconditioning Click here for Project Description Henshall David, RCSI David Henshall, RCSI IRCSET Post-doctoral Fellowship
How does Sterol Modulation influence Seizures and Damage Vulnerability in Epilepsy? Click here for Project Description Henshall David, RCSI - IRCSET Post-doctoral Fellowship
Fas receptor mediates seizure induced neuronal death and epileptogenesis.   Henshall David, RCSI Jochen Prehn, RCSI EU - MarieCurie - re-integration grant - Individual fellowship
A genome-wide DNA methylation analysis of hippocampus from patients with pharmacoresistant temporal lobe epilepsy Click here for Project Description Henshall David, RCSI Norman Delanty, RCSI
Raymond Stallings, RCSI
HRB MRCG/HRB
Role of the ATP-gated P2X7 receptor in neonatal seizures Click here for Project Description Henshall David, RCSI - IRCSET PhD Studentship Programme
Role of Bcl-2-interacting mediator of cell death in seizure-induced brain injury and epileptogenesis.n   Henshall David, RCSI - HRB Equipment Grant
MicroRNAs as Molecular Effectors of Seizure-preconditioning Click here for Project Description Henshall David, RCSI Roger Simon, Morehouse School of Medicine
Raymond Stallings, RCSI
NIH Project Grant
Novel treatments and diagnostics for epilepsy via the ATP-gated P2X7 receptor Click here for Project Description Engel Tobias, RCSI David Henshall, RCSI SFI Starting Investigator Research Grant
The first assessment of multiple histone modifications in brain; an opportunity to identify multiple disease- associated, therapeutically targetable post translational modifications using mass spectrometry. Click here for Project Description Cotter David, RCSI Gerard Cagney, UCD
Mary Cannon, RCSI
Jane English, RCSI
Melanie Foecking, RCSI
David Henshall, RCSI
RCSI Seed Funding
Ultrasensitive Microfliudic Device for the detection of miRNA Targets Associated with Epilepsy Click here for Project Description Henshall David, RCSI Robert Forster, Dublin City University Irish Research Council Postdoctoral Fellowship
Blood adenosine levels as a novel diagnostic of seizures in humans Click here for Project Description Engel Tobias, RCSI Felix Rosenow, Epilepsy Center Frankfurt Rhein-Main, Department of Neurology,
Norman Delanty, RCSI
David Henshall, RCSI
HRB Health Research Award
Regulation of seizure-induced neuronal death by Bcl-2 family proteins   Henshall David, RCSI Brian Harvey, RCSI
Jochen Prehn, RCSI
Wellcome Trust
A new paediatric model to investigate the pathogenesis of mesial temporal lobe epilepsy following seizures in the developing brain Click here for Project Description Henshall David, RCSI David Henshall, RCSI HRB Project Grant
Role of Bcl-2-interacting mediator of cell death in seizure-induced brain injury and epileptogenesis.   Henshall David, RCSI - HRB - Research Project Grants
Targeting the proteasome to prevent seizure-induced neuronal death and epileptogenesis Click here for Project Description Henshall David, RCSI Jose Lucas, Severo Ochoa, Madrid
Norman Delanty, RCSI
HRB Health Research Award
Seizure control in drug-resistant epilepsy by targeting the purinergic P2X7 receptor Click here for Project Description Henshall David, RCSI Miguel Diaz-Hernandez, Univ. Madrid
Roger Simon, Legacy research
Tobias Engel, RCSI
HRB Project Grant
Investigation of death receptor signalling in neuronal death & neuroplastic changes during epilepsy development. (Postdoctoral Fellowship to Dr. Brona Murphy)   Henshall David, RCSI - HRB - Postdoctoral Fellowship Post-doctoral Fellowship
Glycogen synthase kinase -3 as a therapeutic target in seizure-induced neuronal death and epileptogenesis Click here for Project Description Henshall David, RCSI Tobias Engel, RCSI HRB Post-doctoral Research Fellowship
Assessment of the EEG effects of Buproprion HCl vs HBr and histopathological analysis follow-up Click here for Project Description Henshall David, RCSI - Biovail Technologies (Ireland) Ltd
Molecular mechanisms of seizure induced brain injury Click here for Project Description Henshall David, RCSI - Legacy - NIH/NINDS
Molecular mechanisms of seizure induced brain injury Click here for Project Description Henshall David, RCSI - Legacy - NIH/NINDS
A comprehensive analysis of microRNA-124 regulated gene networks and its role in epilepsy Click here for Project Description Henshall David, RCSI David Henshall, RCSI EU-H2020 Marie Curie Post-doctoral Mobility Fellowships
EpiMiRNA: microRNAs in the pathogenesis and treatment of epilepsy Click here for Project Description Henshall David, RCSI - EU-FP7 Collaborative project
Mitochondrial bioenergetics control by the FoxO3 transcription factor Click here for Project Description Henshall David, RCSI - SFI Research Frontiers Programme
microRNA as novel therapeutic targets and disease biomarkers in Alzheimer’s Disease, Frontotemporal dementia and Amyotrophic lateral sclerosis (NEURO-MIR) Click here for Project Description Engel Tobias, RCSI Andre Fischer, DZNE Goettingen
Pierre Lau, VIB Center for the Biology of Disease
Jose Lucas, Centro de Biologia Molecular "Severo Ochoa", Madrid
David Henshall, RCSI
Jochen Prehn, RCSI
SFI COEN
National Biophotonics and Imaging Platform Ireland Click here for Project Description Institute Research, RCSI Brian Harvey, RCSI
David Henshall, RCSI
Cathal Kelly, RCSI
Dermot Kenny, RCSI
Niamh Moran, RCSI
Jochen Prehn, RCSI
Alice Stanton, RCSI
Manus Ward, RCSI
Hugh Byrne, DIT
Noel Caplice, UCC
Kieran McDermott, UCC
Peter Wellstead, NUIM
Peter Dockery, NUIG
Paul Whelan, DCU
Martin Leahy, UL
Patrice Mollard, CNRS
HEA Not Applicable
Molecular determinans of seizure-induced neuronal death & epileptogenesis Click here for Project Description Henshall David, RCSI Raymond Stallings, RCSI SFI Investigator Programme Grants
14-3-3 protein and gene profiling in epileptic brain.   Henshall David, RCSI - NIH/NINDS
Caspases mediate seizure-induced brain injury.   Henshall David, RCSI - NIH/NINDS
Cell excitation in ischemic brain injury.   Henshall David, RCSI - NIH/NINDS
Molecular mechanisms of siezure induced brain injury.   Henshall David, RCSI - NIH/NINDS