AMBER Integra Funded Spoke Project. A bioactive collagen-based conduit for peripheral nerve repair. O’Brien, FJ (PI). €72,691: 2015-2016

Science Foundation Ireland, Maternity Allowance Programme Award. Development of a gene-activated smart scaffold for bone repair. O’Brien FJ (PI). €15,028: 2015-2016.

Horizon 2020, Marie Skłodowska-Curie Individual Fellowship. Temporally controlled delivery of vascular therapeutics from a regenerative template for diabetic wound healing. Kearney, C., O’Brien, FJ. €187,866.

Horizon 2020 European Research Council Grant Proof of Concept Grant. miRNA-activated Scaffold Technologies for Cartilage Regeneration. O’Brien FJ: €149,450.

Temple Street Children’s University Hospital: Children’s Fund for Health Research Grant. Understanding the mechanisms underpinning the influence of age and craniosynostosis on the regenerative capacity of cells and tissues. Murray, D., O’Brien FJ (Co-applicant), Cameron AR; €154,840: 2014-2016.

Irish Research Council, Government of Ireland Postdoctoral Fellowship 2013. Miller G, O’Brien FJ (PI). The development of placental growth factor-functionalised collagen-based scaffolds for promoting vascularisation and bone repair. €91,790: 2014-2016.

Irish Research Council, Government of Ireland Postdoctoral Fellowship 2013. Barreto S, O’Brien FJ (PI). Identification of mechanotransdutive signalling mechanisms associated with age and craniosynostosis with a view to developing advanced bone regeneration strategies. €91,790: 2014-2016.

Enterprise Ireland, Commercialisation Fund Programme. Development of a novel collagen-based film for ocular repair (OcularColl). O’Brien FJ (PI), Cameron A, Clynes M, O’Sullivan F, Murphy C, Power W. €222,705: 2014 - 2016.

Temple Street Children’s University Hospital, Children’s Fund for Health Research Grant. Understanding the mechanisms underpinning the influence of age and craniosynostosis on the regenerative capacity of cells & tissues. Murray, D., O’Brien FJ, Cameron AR; €156,840: 2014-2016.

Enterprise Ireland, Commercialisation Fund Programme: Commercial Case Feasibility Support. Collagen-based thin-film scaffold for closure of tympanic membrane perforations. Cameron, AR, O’Brien, FJ, Barreto, S. €15,000: 2014.

Science Foundation Ireland (SFI) Technology Innovation Development Award Programme (TIDA). The development of a novel construct for peripheral nerve repair. O’Brien FJ (PI), Hibbitts A, Matsiko A, Roche P, Walsh M, Archibald S. €126,852 2014-2015.

Irish Research Council ELEVATE Fellowship 2013. Haugh M, Heilshorn S, O’Brien FJ (Co-applicant). A recombinant approach to cell-matrix interactions and vascular tissue engineering. €238,947: 2014-2016.

Irish Research Council, Government of Ireland Postdoctoral Fellowship 2013. Cameron A, O’Brien FJ (PI). Collagen-based, layer-specific, tissue engineered constructs for partial and full thickness corneal repair. €91,790: 2013-2015.

Irish Research Council, Government of Ireland Postgraduate Scholarship 2013. O’Brien FJ (PI), Lackington W. Advanced scaffold-based therapeutics to facilitate nerve regeneration. €96,000: 2013-2017.

Enterprise Ireland, Commercialisation Fund Programme: Commercial Case Feasibility Support. Development of a novel collagen based film for corneal repair. Cameron AR, O’Brien FJ (PI), €14,900: 2013.

Enterprise Ireland, Commercialisation Fund. Natural ECM derived injectable microparticles for regeneration of the intervertebral disc (DiscReGen) Kelly D, Buckley, C, O’Brien FJ (Co-applicant), Robinson, A. Kiely, P. €135,495: 2013-2014

Science Foundation Ireland (SFI)/ Enterprise Ireland (EI) Joint Technology Innovation Development Award Programme (TIDA). Lopez-Noriega, A, O’Brien, F.J., (Co-applicant). Collagen based scaffolds as a platform for the controlled release of bioactive molecules. €129,169. 2013 - 2014.

Enterprise Ireland, Commercialisation Fund. A novel bioactive scaffold for articular cartilage regeneration. Kelly D, Buckley, C, O’Brien FJ (Co-applicant). €224,851: 2013-2014.

Enterprise Ireland Innovation Partnership (between RCSI and SurgaColl Technologies). Development of novel collagen-based bone and osteochondral graft substitutes for new surgical indications of use. O’Brien FJ (PI), Gleeson JP €246,717. 2012-2016.

Science Foundation Ireland/ Enterprise Ireland Joint Technology Innovation Development Award Programme (TIDA). Development of a novel collagen-based film for corneal repairO’Brien FJ (PI), McCoy R, Clynes M, O’Sullivan F, Murphy C, Power W. . €128,715: 2012-2013.

RCSI/DCU/NUIM Translational Research Hub, Seed Fund Award.  Tissue Engineering/Stem Cell Research Consortium.Coordinators: Fergal O’Brien (RCSI), Finbarr O’Sullivan (DCU), Dr. Kevin Kavanagh (NUIM)  €150,000: 2012-2013.

Enterprise Ireland, Commercialisation Fund.CardioColl, a collagen-alginate composite scaffold to enhance the cardiac stem cell response and promote healing after myocardial infarction Duffy GP, O’Brien FJ (Co-applicant), Gleeson J, Murphy BP. . €673,725: 2012-2014.

AO Foundation, Exploratory Research Project. Porous decellularized hypertrophic tissue engineered cartilage as a scaffold for large bone defect healing.Kelly D, O’Brien FJ (Co-applicant).  €196,750: 2012-2013.

Irish Heart Foundation, John Feely Bursary.Development of a bioreactor test platform to analyse performance of a novel heart valve scaffold. O’Brien FJ (PI), Brougham C.  €3,000: 2012-2013.

Crescent Diagnostics Research Collaboration. Effect of estrogen deficiency on bone structure in a rat OVX model. O’Brien FJ (PI).  €14,250: 2011-2012.

Health Research Board, Project Grant– General.Bone regeneration using stem cell-directed endochondral ossification. O’Brien FJ (PI), Gleeson J.  €298,525: 2011-2014.

Science Foundation Ireland, Research Frontiers Programme. Development of a gene-activated smart scaffold for bone repair.O’Brien FJ (PI), Cryan SA, Kelly H, Duffy G.  €191,300: 2011-2015.

Science Foundation Ireland, Research Frontiers Programme. Development of a cannabinoid-eluting scaffold for orthopaedic tissue engineering strategies.Campbell VA (PI), O’Brien FJ (Co-applicant).  ~ €150,600: 2011-2014.

Enterprise Ireland Commercialisation Fund Commercialisation Plus Phase. Collagen-hydroxyapatite composite scaffolds as bone graft substitutes.O’Brien FJ (PI), Gleeson J.  €82,010: 2011.

Science Foundation Ireland Short Term Travel Fellowship (to the lab of Prof. RE Guldberg, Georgia Institute of Technology).  Investigating the in vivo potential of pre-vascularised collagen based scaffolds for bone tissue regeneration.O’Brien FJ (PI), McFadden T, Guldberg, RE.€10,812: 2011-2012.

Health Research Board, PhD Scholar’s Programme Grant. Diagnostics and Therapeutics in Human Disease. Investigation of the therapeutic potential of stem cells derived from primary amniocentesis for orthopaedic regenerative medicine.O’Brien FJ (PI), Duffy GP (Co-applicant). €104,000: 2011-2014.

Marigot Ltd. Research Grant. Development and evaluation of a novel product to promote osteogenesis. O’Brien FJ (PI).  €30,000: 2011-2012.

Science Foundation Ireland Technology and Innovation Development Award (TIDA). CollAqua: Development of a cell and growth factor free naturally-derived osteoinductive bone graft substitute. O’Brien FJ (PI), O’Gorman D.  € 62,352: 2011-2012.

Health Research Board, PhD Scholar’s Programme Grant. Diagnostics and Therapeutics in Human Disease. Investigation of the angiogenic potential of genetically modified human mesenchymal stem cells. Duffy GP (Principal Investigator), O’Brien FJ (Co-applicant). €104,000: 2010-2013.

European Research Council, Starting Independent Researcher Grant. Collagen-based scaffolds for orthopaedic regenerative medicine: applied biomaterials, bioreactor and stem cell technology. O’Brien FJ (Sole Applicant and PI).  €1,999,531: 2010-2014.

Enterprise Ireland Commercialisation Fund, Proof of Concept Phase Grant. Development of a bi-layered cardiac scaffold to enhance the natural cardiac stem cell response in cardiovascular disease and the onset of heart failure. Duffy GP, O’Brien FJ (Co-applicant).  €101,480: 2009-2010.

Enterprise Ireland Commercialisation Fund, Commercialisation Fund Technology Development Phase.  Collagen scaffold-based system for gene and drug delivery to facilitate bone tissue repair (TheraColl). O’Brien FJ (Principal Investigator), Partap S, Gleeson J, Duffy G, Kelly H. €395,153: 2009-2012.

Health Research Board PhD Scholars Programme Grant, ‘Diagnostics and Therapeutics in Human Disease’: Vascularisation within a collagen-GAG scaffold with human mesenchymal stem cells. O’Brien FJ (Principal Investigator), Duffy GP (Co-applicant).  €104,000: 2009-2012.

Health Research Board Clinical Research Training Fellowship. The in vivo response of engineered collagen-calcium phosphate scaffolds combined with bone morphogenic protein for orthopaedic regenerative medicine. Lyons, F., O’Brien, F.J., (Co-applicant). €151,428: 2009-2011.

Irish Research Council for Science, Engineering and Technology: INSPIRE: - Marie Curie International Mobility Fellowship. Mechanosensitive primary cilia in osteogenic differentiation of stem cells due to loading. Hoey D, Jacobs C, O’Brien FJ (Co-applicant). €243,888: 2009-2012.

Enterprise Ireland Commercialisation Fund, Commercialisation Fund Technology Development Phase.  Polyphasic collagen-based composite scaffolds for osteochondral defect repair. Gleeson J, Levingstone T, O’Brien FJ (Co-applicant). €400,242: 2009-2012

Health Research Board PhD Scholars Programme Grant, ‘Diagnostics and Therapeutics in Human Disease’: Changes in the ultrastructural design features of osteoporotic bone. Lee TC (Principal Investigator), O’Brien FJ (Co-applicant). €104,000: 2008-2011.

Enterprise Ireland Commercialisation Fund, Proof of Concept Phase Grant. Novel osteoinductive composite scaffolds for BMP delivery for bone tissue repair.  O’Brien FJ (Principal Investigator), Gleeson J. €84,679: 2008-2009.

Science Foundation Ireland, Research Frontiers Programme. Molecular mechanisms underlying staphylococcal induced osteomyelitis.  Kerrigan S, O’Brien FJ (Co-applicant), Foster T. €186,600: 2008-2011.

Enterprise Ireland Commercialisation Fund, Proof of Concept Phase Grant. Polyphasic collagen-based composite scaffolds for osteochondral defect repair.  Gleeson J, O’Brien FJ (Co-applicant). €81,668: 2008-2009.

Science Foundation Ireland Supplementary Equipment Grant.  In vivo and in vitro imaging system spectrum series. Harmey J, O’Brien FJ (Co-applicant), Stallings R, Jefferies C, Henshall D, O’Tuathaigh C. €332,931

Science Foundation Ireland Supplementary Equipment Grant. Digital epifluorescence microscope with high resolution camera system and image analysis workstation. O’Brien FJ (Principal Investigator), Kelly D, Campbell VA, Harmey J, Jefferies C. €74,997

Enterprise Ireland Commercialisation Fund, Proof of Concept Phase Grant. Design and development of a novel device to control the fabrication, confined compression and in situ delivery of cell-seeded collagen gel scaffolds. Kelly D, O’Brien FJ (Co-applicant), Mulhall K. €99,640: 2008-2009.

Enterprise Ireland Commercialisation Fund Technology Development Phase (TDP). Collagen-hydroxyapatite composite scaffolds as bone graft substitutes. O’Brien FJ (Principal Investigator), Gleeson J.  €410,841: 2007-2010.

Health Research Board, Project Grant – General. Bone tissue mineralization during osteoporosis. O’Brien FJ (Principal Investigator), McNamara L.  €313,229: 2007-2010.

Science Foundation Ireland, Research Frontiers Programme. Induction of in vitro angiogenesis by marrow stromal cells on collagen glycosaminoglycan scaffolds for orthopaedic tissue engineering. O’Brien, F.J., (PI), Campbell, V.A., Farrell, E., Prendergast, P.J.  €222,526: 2007-2010.

Science Foundation Ireland, Research Frontiers Programme. Influence of biophysical stimuli on tissue differentiation and matrix synthesis in vitro.  Kelly D, O’Brien FJ (Co-applicant), Campbell VA. €171,750: 2007-2010.

Science Foundation Ireland, Research Frontiers Programme. Is the bone tissue mineralization process altered during osteoporosis?  McNamara L, O’Brien FJ (Co-applicant), Campbell VA. €179,311: 2007-2010.

Enterprise Ireland Commercialisation Fund, Proof of Concept Phase Grant. Novel device to control in situ the thermal gelation and concentration of cell-seeded hydrogels.  Kelly D, O’Brien FJ (Co-applicant), Robinson A. €92,945: 2007-2009.

Science Foundation Ireland, Industry Research Partnership Supplement Application. Computational modelling of the pore structure, permeability and mechanical behaviour of collagen-GAG scaffolds for bone tissue engineering. O’Brien FJ (Principal Applicant). €210,000: 2007-2009.

Science Foundation Ireland, Research Frontiers Programme. Development of a novel bone graft substitute. O’Brien FJ (Principal Investigator), Dickson GR. €139,900: 2006-2009.

Enterprise Ireland Commercialisation Fund, Proof of Concept Phase Grant. Collagen-hydroxyapatite composite scaffolds as bone graft substitutes.  O’Brien FJ (Sole Applicant & Principal Investigator). €68,913: 2006-2007.

Embark, Irish Research Council for Science, Engineering and Technology, Postgraduate Scholarship Scheme. Collagen-calcium phosphate scaffolds for bone tissue engineering. O’Brien FJ (Principal Applicant), Plunkett N. €80,914: 2005-2008.

Royal College of Surgeons in Ireland, Research Committee Grant. Development of a bone graft substitute: molecular analysis of osteogenesis by human osteoblasts on a three dimensional collagen scaffold.  Daly J, O’Brien FJ (Co-applicant). €90,000: 2005-2008:

Health Research Board, Basic Research Grant. Tissue engineering of cartilage and bone in an hypoxic environment. Campbell VA, O’Brien FJ (Co-applicant), Prendergast PJ.  €155,000: 2005-2008.

Science Foundation Ireland, President of Ireland Young Researcher Award. Tissue engineering for orthopaedic applications: the use of collagen scaffolds for the development of bone graft substitutes. O’Brien FJ (Sole Applicant and PI). €1.1 million: 2004-2009.

Health Research Board, Equipment Grant. Automatic tissue processor for histology applications. O’Brien FJ (Principal Applicant), Lee TC, Rackard SM. €27,528: 2004-2007.

Health Research Board, Basic Research Grant. Role of microcracks in targeted bone remodeling and their relationship with bone fragility and osteoporosis. O’Brien FJ (Principal Applicant), Lee TC, Rackard SM. €112,800: 2004-2007.

Irish-American Fulbright Commission: Fulbright Scholarship. Orthopaedic biomaterials and tissue engineering. O’Brien FJ (Sole Applicant). IR£10,000: 2001-2003