2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2001 | All

Rodriguez-Alvarez N, Jimenez-Mateos EM, Dunleavy M, Waddington JL, Boylan GB, Henshall DC .
Effects of hypoxia-induced neonatal seizures on acute hippocampal injury and later-life seizure susceptibility and anxiety-related behavior in mice.
Neurobiol Dis. 2015;83:100-114.     PMID: 26341542      (Sep 2015)

Sukno FM, Waddington JL, Whelan PF .
3-D facial landmark localization with asymmetry patterns and shape regression from incomplete local features.
IEEE Trans Cybern. 2015;45(9):1717-30.     PMID: 25314716      (Sep 2015)

Turner N, O’Mahony P, Hill M, Fanning F, Larkin C, Waddington J, O'Callaghan E, Clarke M. .
Work life after psychosis: a detailed examination.
WORK. 2015;51(1):143-152.     PMID: 24894690      (Jun 2015)

Turner N, O’Mahony P, Hill M, Fanning F, Larkin C, Waddington J, O'Callaghan E, Clarke M .
Work life after psychosis: a detailed examination.
WORK. 2015;51(1):143-152     PMID: 24894690      (Jun 2015)

Jiang L, O’Leary C, Kim HA, Parish CL, Massalas J, Waddington JL, Ehrlich ME, Schutz G, Gantois I, Lawrence AJ, Drago J .
Motor and behavioural phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cells.
Neurobiol Dis. 2015;76:137-58.     PMID: 2568453      (Apr 2015)

Nkiri N, Sardinha S, Nwosu B, McDonough CM, De Coteau PA, Duffy I, Waddington JL, Russell V .
Evaluation of knowledge and attitudes among primary care physicians in Cavan-Monaghan as 'gatekeepers-in-waiting' for the introduction of Carepath for Overcoming Psychosis Early (COPE).
Early Interv Psychiatry. 2015;9(2):141-50.     PMID: 23855315      (Apr 2015)

Prasad S, Katina S, Hennessy RJ, Murphy KC, Bowman AJ, Waddington JL .
Craniofacial dysmorphology in 22q11.2 deletion syndrome by 3D laser surface imaging and geometric morphometrics: illuminating the developmental relationship to risk for psychosis.
Am J Med Genet A. 2015;167A(3):529-36.     PMID: 25691406      (Mar 2015)

Ikeda H, Adachi K, Fujita S, Tomiyama K, Saigusa T, Kobayashi M, Koshikawa N, Waddington JL .
Investigating complex basal ganglia circuitry in the regulation of motor behaviour, with particular focus on orofacial movement.
Behav Pharmacol. 2015;26(1-2):18-32.     PMID: 25485640      (Feb 2015)

O’Tuathaigh CM, Waddington JL .
Closing the translational gap between mutant mouse models and the clinical reality of psychotic illness.
Neurosci Biobehav Rev. 2015; Epub ahead of print.     PMID: 25616181      (Jan 2015)

Fountoulakis KN et al including Grady A, Waddington J .
Relationship of suicide rates to economic variables in Europe: 2000-2011.
Br J Psychiatry. 2014; 205:486-96.     PMID: 25359926      (Dec 2014)

Gusev A, et al including Waddington J .
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Am J Hum Genet. 2014;95(5):535-52     PMID: 25439723      (Nov 2014)

O'Callaghan MJ, Bay-Richter C, O'Tuathaigh CM, Heery DM, Waddington JL, Moran PM .
Potentiation of latent inhibition by haloperidol and clozapine is attenuated in dopamine D2 receptor (Drd-2)-deficient mice: Do antipsychotics influence learning to ignore irrelevant stimuli via both Drd-2 and non-Drd-2 mechanisms?
J Psychopharmacol. 2014;28:973-7.     PMID: 25122042      (Oct 2014)

O’Leary C, Desbonnet L, Clarke N, Petit E, Tighe O, Lai D, Harvey R, Waddington JL. O’Tuathaigh, C .
Phenotypic effects of maternal immune activation and early postnatal milieu in mice mutant for the schizophrenia risk gene neuregulin-1.
Neuroscience 2014; 277, 294-305.     PMID: 24969132      (Sep 2014)

Schizophrenia Working Group of the Psychiatric Genomics Consortium (including Waddington J) .
Biological insights from 108 schizophrenia-associated genetic loci.
Nature. 2014;511:421-7.     PMID: 25056061      (Jul 2014)

O'Tuathaigh CM, Gantois I, Waddington JL .
Genetic dissection of the psychotomimetic effects of cannabinoid exposure.
Prog. Neuropsychopharmacol. Biol. Psychiatry 2014;52:33-40.     PMID: 24239593      (Jul 2014)

Morris DW, Pearson RD, Cormican P, Kenny EM, O'Dushlaine CT, Lemieux Perreault LP, inc., Waddington JL, et al; International Schizophrenia Consortium; SGENE+ Consortium, Wellcome Trust Case Control Consortium 2, Kendler KS, Gill M, Riley BP, Spencer CC, Corvin A .
An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.
Hum Mol Genet. 2014;23:3316-26.     PMID: 24474471      (Jun 2014)

O'Tuathaigh CM, Desbonnet L, Waddington JL .
Genetically modified mice related to schizophrenia and other psychoses: Seeking phenotypic insights into the pathobiology and treatment of negative symptoms.
Eur. Neuropsychopharmacol. 2014;24:800-821.     PMID: 24290531      (May 2014)

Kim HA, Jiang L, Madsen H, Parish CL, Massalas J, Smardencas A, O'Leary C, Gantois I, O'Tuathaigh C, Waddington JL, Ehrlich ME, Lawrence AJ, Drago J .
Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells.
Neurobiol Dis. 2014;62:323-37.     PMID: 24135007      (Feb 2014)

Omer S, Kirkbride JB, Pringle DG, Russell V, O'Callaghan E, Waddington JL .
Neighbourhood-level socio-environmental factors and incidence of first episode psychosis by place at onset in rural Ireland: The Cavan-Monaghan First Episode Psychosis Study CAMFEPS.
Schizophr. Res. 2014;152:152-157.     PMID: 24342585      (Jan 2014)

Mullin AP, Gokhale A, Moreno-De-Luca A, Sanyal. S, Waddington JL, Faundez V .
Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes.
Transl Psychiatry. 2013;3:e329     PMID: 24301647      (Dec 2013)

Kingston T, Scully PJ, Browne DJ, Baldwin PA, Kinsella A, Russell V, O'Callaghan E. & Waddington JL .
Diagnostic trajectory, interplay and convergence/divergence across all 12 DSM-IV psychotic diagnoses: 6-year follow-up of the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS).
Psychol. Med. 2013;1-11.     PMID: 23480983      (Dec 2013)

Tomiyama K, Kato R, Hara Y, Kobayashi M, Mishina M, Yanagawa Y, Kinsella A, Koshikawa N. & Waddington JL .
Phenotypic characterization of orofacial movement topography in mutants with disruption of amino acid mechanisms: Glutamate N2A/B/D GluRå1/2/4 subtypes and the GABA synthesizing enzyme GAD65.
Neuroscience 2013;250:743-54     PMID: 23892010      (Oct 2013)

O'Tuathaigh CM, Moran PM. & Waddington JL .
Genetic models of schizophrenia and related psychotic disorders: progress and pitfalls across the methodological 'minefield'.
Cell Tissue Res. 2013;354:247-257.     PMID: 23715722      (Oct 2013)

Waddington JL, Buckley PF .
Psychotic depression: an under-appreciated window to explore the dimensionality and pathobiology of psychosis.
Schizophr Bull. 2013;39:754-755.     PMID: 23709405      (Jul 2013)

Owoeye O, Kingston T, Scully PJ, Baldwin P, Browne D, Kinsella A, Russell V, O'Callaghan E, Waddington JL .
Epidemiological and clinical characterisation following a first psychotic episode in major depressive disorder: comparisons with schizophrenia and bipolar disorder.
Schizophr Bull. 2013;39:756-765.     PMID: 23716714      (Jul 2013)

Sukno FM, Waddington JL. & Whelan PF .
Rotationally invariant 3D shape contexts using asymmetry patterns.
In: Proc. 8th International Conference on Computer Graphics Theory and Applications, Barcelona, Spain, pp 7-17, 2013.     PMID: n/a      (Jun 2013)

Sukno F M, Waddington JL. & Whelan PF .
Craniofacial landmark localisation with asymmetry patterns shape objects.
In: BioPIC 2013 BioPhotonics and Imagining conference, Dublin, Ireland, pp 25-27, 2013     PMID: n/a      (Jun 2013)

Sukno FM, Waddington JL. & Whelan PF .
Compensating inaccurate annotations to train 3D facial landmark localization models.
In: Proc. Workshop on 3D Face Biometrics, Shanghai, China, IEEE Xplore Digital Library, pp 1-8, 2013.     PMID: n/a      (Jun 2013)

Sukno FM, Waddington JL. & Whelan PF .
3D Facial landmark localization using combinatorial search and shape regression.
In: (Bebis, G. et al, Eds.) Computer Vision - ECCV Springer-Verlag, Berlin 2012;7583, pp 32-41.     PMID: N/A      (May 2013)

Kingston T, Scully PJ, Browne DJ, Baldwin PA, Kinsella A, Russell V, O'Callaghan E. & Waddington JL .
Diagnostic trajectory, interplay and convergence/divergence across all 12 DSM-IV psychotic diagnoses: 6-year follow-up of the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS).
Psychol Med. 2013;1-11.     PMID: 23480983      (Mar 2013)

Bay-Richter C, O'Callaghan MJ, Mathur N, O'Tuathaigh CM, Heery DM, Fone KC, Waddington JL, & Moran PM .
D-amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D2 receptors.
Neuropsychopharmacology 2013;38:1512-1520.     PMID: 23422792      (Feb 2013)

Cummings E, Donohoe G, Hargreaves A, Moore S, Fahey C, Dinan TG, McDonald C, O'Callaghan E, O'Neill FA, Waddington JL, Murphy KC, Morris DW, Gill M. & Corvin A .
Mood congruent psychotic symptoms and specific cognitive deficits in carriers of the novel schizophrenia risk variant at MIR-137.
Neurosci Lett. 2013;532:33-8.     PMID: 22982201      (Jan 2013)

van der Werf M, Hanssen M, Köhler S, Verkaaik M. & Verhey FR. RISE Investigators including Baldwin P. & Waddington JL, van Winkel R, van Os J, Allardyce J .
Systematic review and collaborative recalculation of 133 693 incident cases of schizophrenia.
Psychol Med. 2012;1-8.     PMID: 23244442      (Dec 2012)

Desbonnet L, O’Tuathaigh CMP. & Waddington JL .
Modelling schizophrenia: uncovering novel therapeutic targets.
Exp Rev Clin Pharmacol. 2012;5:667-76.     PMID: 23234324      (Nov 2012)

Hill M, Crumlish N, Whitty P, Clarke M, Browne S, Gervin M, Macklin E, Kinsella A, Larkin C, Waddington JL, O’Callaghan E .
Prospective relationship of duration of untreated psychosis to psychopathology and functional outcome over 12 years.
Schizophr Res. 2012; 141(2-3):215-21.     PMID: 23006501      (Nov 2012)

O'Tuathaigh CMP, Clarke G, Walsh J, Desbonnet L, Petit E, O'Leary C, Tighe O, Karayiorgou M, Gogos JA, Dinan TD, Cryan J, Waddington JL .
Genetic vs pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes.
Int J Neuropsychopharmacol. 2012;15:1331-42     PMID: 22074909      (Oct 2012)

Tomiyama K, Drago J, Waddington JL, Koshikawa N .
Constitutive and conditional mutant mouse models for understanding dopaminergic regulation of orofacial movements: emerging insights and challenges.
J Pharmacol. Sci. 2012;119: 297-301.     PMID: 22863668      (Aug 2012)

Irish Schizophrenia Genomics Consortium including Waddington JL and the Wellcome Trust Case Control Consortium 2 .
Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.
Biol Psychiatry. 2012;72:620–628.     PMID: 22883433      (Aug 2012)

Adachi K, Kobayashi M, Kawasaki T, Yokoyama C, Waddington JL, Sakagami H, Onoe H, Koshikawa N .
Disruption of programmed masticatory movements in unilateral MPTP-treated monkeys as a model of jaw movement abnormality in Parkinson's disease.
J Neural Transm. 2012;119:933-41.     PMID: 22350537      (Aug 2012)

Jimenez-Mateos E M, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, Sano T, O'Tuathaigh C, Waddington JL, Prenter S, Delanty N, Farrell MA, O'Brien DF, Conroy RM, Stallings RL, Defelipe J, Henshall DC .
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects.
Nat. Med. 2012; 18:1087-1094.     PMID: 22683779      (Jul 2012)

Desbonnet L, O'Tuathaigh C, Clarke G, O'Leary C, Petit E, Clarke N, Tighe O, Lai D, Harvey N, Cryan JF, Dinan TG, Waddington JL .
Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: a putative model of gene × environment interaction.
Brain Behav Immun. 2012;26:660-671.     PMID: 22426432      (May 2012)

O'Tuathaigh CM, Desbonnet L, Moran PM, Waddington JL .
Susceptibility genes for schizophrenia: mutant models, endophenotypes and psychobiology.
Curr Top Behav Neurosci. 2012; 12: 209-50.     PMID: 22367925      (May 2012)

Behan AT, Hryniewiecka M, O’Tuathaigh CMP, Kinsella A, Cannon M, Karayiorgou M, Gogos JA, Waddington JL, Cotter DR .
Chronic adolescent exposure to delta-9-tetrahydrocannabinol in COMT mutant mice: impact on indices of dopaminergic, endocannabinoid and GABAergic pathways.
Neuropsychopharmacol. 2012;37(7):1773-83     PMID: 22434221      (May 2012)

O'Tuathaigh CMP, Desbonnet L, Lee P, Waddington JL .
Catechol-O-methyltransferase as a drug target for schizophrenia.
CNS & Neurol Disord Drug Targets. 2012;11(3), 282-91.     PMID: 22483298      (May 2012)

Desbonnet L, Tighe O, Tarayiorgou M, Gogos JA, Waddington JL, O'Tuathaigh CM .
Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice.
Behav Brain Res. 2012;228(2):351-8.     PMID: 22192380      (Mar 2012)

Walsh J, Desbonnet L, Clarke N, Waddington JL, O'Tuathaigh CMP. .
Disruption of exploratory and habituation behavior in mice with mutation of DISC1: an ethologically based analysis.
J Neurocsi Res. 2012;90(7):1445-53.     PMID: 22388794      (Dec 2011)

Runker AE, O'Tuathaigh CM, Dunleavy M, Morris DW, Little GE, Corvin AP, Gill M, Henshall DC, Waddington JL, Mitchell KJ. .
Mutation of semaphorin-6A disrupts limbic and cortical connectivity and models neurodevelopmental psychopathology.
PLoS One 6:26488, 2011.     PMID: 22132072      (Nov 2011)

Kas MJ, Kahn RS, Collier DA, Waddington JL, Ekelund J, Porteous DJ, Schughart K, & Hovatta I. .
Translational neuroscience of schizophrenia: seeking a meeting of minds between mouse and man.
Science Transl Med. 2011;3:102mr3.     PMID: 21957171      (Sep 2011)

Waddington JL, Hennessy, RJ, O'Tuathaigh CMP, Owoeye O, & Russell V. .
Schizophrenia and the lifetime trajectory of psychotic illness: developmental neuroscience and pathobiology, redue.
In: The Origins of Schizophrenia (A.S. Brown & P.H. Harrison Eds), Columbia University Press, New York). 2012; pp 3 - 12.     PMID: doi:10.1017/S1461145711001581      (Sep 2011)

Tomiyama K, O’Tuathaigh CMP, Waddington JL. .
Regulation of orofacial movement: amino acid mechanisms and mutant models.
Int Rev Neurobiol. 2011;97:61-75.     PMID: 21708307      (Sep 2011)

Waddington JL, O’Sullivan GJ, Tomiyama K. .
Regulation of orofacial movement: dopamine receptor mechanisms and mutant models
Int Rev Neurobiol. 2011;97:39-60.     PMID: 21708306      (Sep 2011)

O'Tuathaigh CM, Desbonnet L. Moran PM, Kirby BP, Waddington JL. .
Molecular genetic models related to schizophrenia and psychotic illness: heuristics and challenges.
Curr Top Behav Neurosci. 2011;7:87-119.     PMID: 21298380      (Jun 2011)

Gangarossa G, Di Benedetto M, O'Sullivan GJ, Dunleavy M, Alcacer C, Bonito-Oliva A, Henshall DC, Waddington Jl, Valjent E, Fisone G. .
Convulsant doses of a dopamine d1 receptor agonist result in erk-dependent increases in zif268 and aarc/arg3.1 expression in mouse dentate gyrus.
PLoS One 6:e19415.     PMID: 21559295      (May 2011)

Waddington JL, O’Tuathaigh CM, & Remington GJ. .
The pharmacology and neuroscience of antipsychotic drugs.
In: Schizophrenia, Third Edition (D.R. Weinberger & P.J. Harrison, Eds), Wiley-Blackwell, Oxford. 2010; pp. 485-514.     PMID: DOI: 10.1002/9781444327298      (Mar 2011)

Hill M, Crumlish N, Whitty P, Clarke M, Browne S, Gervin M, Kinsella A, Waddington JL, larkin C, O'Callaghan E. .
The relationship between insight and neurological dysfunction in first-episode psychosis.
Eur Psychiatry. 2012; 27, 200-205.     PMID: 21392944      (Mar 2011)

Tomiyama K, Kim HA, Kinsella A, Ehrlich ME, Schutz G, Koshikawa N, Lawrence AJ, Waddington JL, Drago J. .
Phenotypic disruption to orofacial movement topography in conditional mutants with generalised CamKlla/Cre D1Tox versus striatal-specific DARPP-32/Cre D1Tox ablation of D1 dopamine receptor-expressing cells.
Synapse 2011;65:835-42.     PMID: 21308794      (Jan 2011)

O'Tuathaigh CM, Hryniewiecka M, Behan A, Tighe O, Coughlan C, Desbonnet L, Cannon M, Karayiorgou M, Gogos JA, Cotter DR, Waddington JL. .
Chronic adolescent exposure to ∆-9-tetrahydrocannabinol in COMT mutant mice:impact on psychosis-related and other phenotypes.
Neuropsychopharmacol. 2010;35:2262-73.     PMID: 20631688      (Oct 2010)

Kirby BP, Waddington JL, O'Tuathaigh CM. .
Advancing a functional genomics for schizophrenia: psychopathological and cognitive phenotypes in mutants with gene disruption. Advancing a functional genomics for schizophrenia: Psychopathological and cognitive phenotypes in mutants with gene disruption.
Brain Res Bull. 2010;83(3-4):162-76.     PMID: 19800398      (Sep 2010)

Raychaudhuri S, Korn JM, McCarroll SA; International Schizophrenia Consortium [including Waddington JL], Altshuler D, Sklar P, Purcell S, Daly MJ. .
Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.
PLoS Genet. 2010;6(9). pii: e1001097.     PMID: 20838587      (Sep 2010)

Cummings E, Donohoe G, McDonald C, Dinan TG, O'Neill FA, O'Callaghan E, Waddington JL, Murphy KC, Gill M, Morris DW, Corvin A .
Clinical symptomatology and the psychosis risk gene ZNF804A.
Schizophr Res. 2010;122(1-3):273-5.     PMID: 20538430.      (Sep 2010)

Hennessy RJ, Baldwin PA, Browne DJ, Kinsella A, Waddington JL. .
Frontonasal dysmorphlogy in bipolar disorder by 3D laser surface imaging and geometric morphometrics: comparisons with schizophrenia.
Schizophr Res. 2010;122:63-71.     PMID: 20554158      (Sep 2010)

Walsh J, Tighe O, Lai D, Harvey R, Karayiorgou M, Gogos JA, Waddington JL, O'Tuathaigh CM. .
Disruption of thermal nociceptive behaviour in mice mutant for the schizophrenia-associated genes NRG1, COMT and DISC1.
Brain Res. 2012;1348:114-9.     PMID: 20561508      (Aug 2010)

Fujita S, Kiguchi M, Kobayashi M, Kinsella A, Koshikawa N. & Waddington JL. .
Assessment of jaw movements by magnetic sensor in relation to topographies of orofacial behaviour in freely moving rats: Studies with the dopamine D(1)-like receptor agonists SKF 83822 vs SKF 83959.
Eur J Pharmacol. 2010;632(1-3):39-44.     PMID: 20122923      (Apr 2010)

O'Tuathaigh CM, Kirby BP, Moran PM. & Waddington JL. .
Mutant Mouse Models: Genotype-phenotype relationships to negative symptoms in schizophrenia.
Schizophr Bull. 2010;36:271-88.     PMID: 19934211      (Mar 2010)

Fujita S, Kiguchi M, Kobayashi M, Koshikawa N, Waddington JL. .
Involvement of NMDA receptors in the ventrolateral striatum of rats in apomorphine-induced jaw movements.
Brain Research 2010;1322:30-7.     PMID: 220122906      (Mar 2010)

Tomiyama K, Song L, Kobayashi M, Kinsella A, Kanematsu T, Hirata M, Koshikawa N, Waddington JL. .
Orofacial movements in phospholipase C-related catalytically inactive protein (PRIP)-1/2 double knockout mice: effect of the GABAergic agent diazepam and the D(1) dopamine receptor agonist SKF 83959.
Synapse 2010;64:714-20.     PMID: 20340178      (Mar 2010)

Waddington JL, O’Tuathaigh CM. & Remington GJ .
Second-generation antipsychotic drugs: mechanistically distinct or minor variants?
In: Therapeutic Strategies in Schizophrenia (A. Mortimer, & P. McKenna, Eds), Clinical Publishing, Oxford, pp 207-216, 2011.     PMID: n/a      (Mar 2010)

Omer S, Behan C, Waddington JL, O’Callaghan E. .
Early intervention in pssychosis: service models worldwide and the Irish experience.
Ir J Psychol Med. 2010;27(4):210-214.     PMID: n/a      (Feb 2010)

Hill M, Crumlish N, Whitty P, Clarke M, Browne S, Kamali M, Kinsella A, Waddington JL, Larkin C, O’Callaghan E. .
Nonadherence to medication four years after a first episode of psychosis and associated risk factors.
Psychiatr Serv. 2010; 61(2):189-92.     PMID: 20123826      (Feb 2010)

O’Tuathaigh, CM, Waddington JL. .
Mutant mouse models: phenotypic relationships to domains of psychopathology and pathobiology in schizophrenia. .
Schizophr Bull. 2010;36:243-5. Epub 2010 Feb 12.     PMID: 20154202      (Feb 2010)

Kelly BD, O'Callaghan E, Waddington JL, Feeney L, Browne S, Scully PJ, Clarke M, Quinn JF, McTigue O, Morgan MG, Kinsella A, Larkin C. .
Schizophrenia and the city: A review of literature and prospective study of psychosis and urbanicity in Ireland.
Schizophr Res. 2010;116(1):75-89.     PMID: 19897342      (Jan 2010)

Roche E, Clarke M, Browne S, Turner N, McTuige O, Kamali M, Kinsellia A, Larkin C, Waddington JL, & O’Callaghan, E. .
Prevalence and clinical correlates of depression in the acute phase of first episode schizophrenia.
Ir J Psych Med. 2010; 27, 15-18.     PMID: n/a      (Jan 2010)

Babovic D, Jiang L, Gantois I, Lawrence AJ, Ferreri V, Schutz G, Waddington JL. & Drago J. .
Age-related behavioural phenotype and cellular characterisation of mice with progressive ablation of D1 dopamine receptor-expressing cells.
Behav Brain Res. 2010;206:78-87.     PMID: 19733597      (Jan 2010)

O’Sullivan GJ, O’Tuathaigh CM, Tomiyama K, Koshikawa, A. & Waddington JL. .
Dopamine receptors and behavior: from psychopharmacology to mutant models.
In: The Dopamine Receptors (K. Neve, Ed), Humana Press, Totawa, NJ,     PMID: pp 323-371, 2010.      (Jan 2010)

O'Tuathaigh CM, Harte M, O'Leary C, O'Sullivan GJ, Blau C, Lai D, Harvey RP, Tighe O, Fagan AJ, Kerskens C, Reynolds GP, Waddington JL. .
Schizophrenia-related endophenotypes in heterozygous neuregulin-1 'knockout' mice.
Eur J Neurosci. 2010;31(2):349-58.     PMID: 20074216      (Jan 2010)

Desbonnet L, Waddington JL. & O’Tuathaigh CM. .
Mice mutant for genes associated with schizophrenia: Common phenotype or distinct endophenotypes?
Behav Brain Res. 2009;204(2):258-73.     PMID: 19728400      (Dec 2009)

Desbonnet L, Tomiyama K, Koshikawa N, O’Tuathaigh CM. & Waddington JL .
Mutant and transgenic tools in modelling schizophrenia. In: Transgenic and Mutant Tools to Model Brain Disorders (A.V. Kalueff, Ed), Humana Press, Totawa, NJ
pp 217-239, 2010.     PMID: DOI: 10.1007/978-1-60761-474-6_12      (Nov 2009)

Turner, N., Browne, S., Clarke, M., Gervin, M., Larkin, C., Waddington, J.L. & O’Callaghan, E. .
Employment status among those with psychosis at first presentation.
Soc Psychiat Psychiatric Epidemiol. 2009;44(10):863-9.     PMID: 19255700      (Oct 2009)

Bay-Richter C, O'Tuathaigh CM, O'Sullivan G, Heery DM, Waddington JL, Moran PM. .
Enhanced latent inhibition in dopamine receptor-deficient mice is sex-specific for the D1 but not D2 receptor subtype: implications for antipsychotic drug action.
Int J Neuropsychopharmacol. 2009;12:403-14.     PMID: 19012810      (Apr 2009)

Tomiyama K, O’Tuathaigh CM, O’Sullivan GJ, Kinsella A, Lai D, Harvey RP, Tighe O, Croke DT, Koshikawa, N. & Waddington JL. .
Phenotype of spontaneous orofacial dyskinesia in neuregulin-1 ‘knockout’mice. Prog. Neuropsychopharmacol.
Biol Psychiatry. 2009;33(2):330-3.     PMID: 19150478      (Mar 2009)

Whitty PF, Owoeye O. & Waddington JL. .
Neurological signs and involuntary movements in schizophrenia: intrinsic to and informative on systems pathobiology.
Schizophr. Bull. 2009;35(2):415-24.     PMID: 18791074      (Mar 2009)

Desbonnet L, Waddington JL. & O’Tuathaigh CM. .
Mutant models for genes associated with schizophrenia.
Biochem. Soc. Trans. 2009;37(Pt 1):308-12.     PMID: 19143653      (Feb 2009)

Crumlish N, Whitty P, Clarke M, Browne S, Kamali M, Gervin M, McTigue O, Kinsella A, Waddington JL, Larkin C. & O’Callaghan, E. .
Beyond the critical period: longitudinal study of 8-year outcome in first-episode non-affective psychosis.
Br. J. Psychiatry, 2009;194(1):18-24.     PMID: 19118320      (Jan 2009)

O’Tuathaigh CM, Desbonnet L. & Waddington JL. .
Neuregulin-1 signaling in schizophrenia: ‘Jack of all trades’ or master of some ?
Expert Rev Neurother. 2009;9(1):1-3.     PMID: 19102663      (Jan 2009)

Owoeye O, Kingston T, Hennessy RJ, Baldwin PA, Browne D, Scully PJ, Kinsella A, Russell V, O’Callaghan E. & Waddington JL .
The ‘totality’ of psychosis: epidemiology and developmental pathobiology. In: Search for the Causes of Schizophrenia (W.F. Gattaz & G. Busatto, Eds), Springer, New York
2010; pp 377-385.     PMID: DOI: 10.1007/978-1-4419-0913-8_21      (Jan 2009)

International Schizophrenia Consortium [including Waddington JL]. .
Rare chromosomal deletions and duplications increase risk of schizophrenia.
Nature. 2008;455(7210):237-41. Epub 2008 Jul 30.     PMID: 18668038      (Sep 2008)

Babovic D, O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL .
Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase.
Neuroscience. 2008;155(4):1021-9.     PMID: 18674597      (Sep 2008)

Yang MS, Morris DW, Donohoe G, Kenny E, O'Dushalaine CT, Schwaiger S, Nangle JM, Clarke S, Scully P, Quinn J, Meagher D, Baldwin P, Crumlish N, O'Callaghan E, Waddington JL, Gill M, Corvin A. .
Chitinase-3-like 1 (CHI3L1) gene and schizophrenia: genetic association and a potential functional mechanism.
Biol Psychiatry. 2008;64(2):98-103.     PMID: 18281018      (Jul 2008)

O'Sullivan GJ, Dunleavy M, Hakansson K, Clementi M, Kinsella A, Croke DT, Drago J, Fienberg AA, Greengard P, Sibley DR, Fisone G, Henshall DC, Waddington JL .
Dopamine D1 vs D5 receptor-dependent induction of seizures in relation to DARPP-32, ERK1/2 and GluR1-AMPA signalling.
Neuropharmacology. 2008;54(7):1051-61.     PMID: 18367215      (Jun 2008)

Waddington JL, Brown AS, Lane A, Schaefer CA, Goetz RR, Bresnahan M, Susser ES. .
Congenital anomalies and early functional impairments in a prospective birth cohort: risk of schizophrenia-spectrum disorder in adulthood.
Br J Psychiatry. 2008;192(4):264-7.     PMID: 18378985      (Apr 2008)

Jackson D, Lawoyin R, Gaynor K, Clarke M, Browne S, Renwick L, Sutton M, Turner N, Kinsella A, Waddington JL, Larkin C, Callaghan EO. .
Is the duration of untreated psychosis temporally stable?
Eur Psychiatry. 2008;23(2):97-9.     PMID: 17945469      (Mar 2008)

O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Lai D, Harvey R, Croke DT, Waddington JL. .
Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous 'knockout' of the schizophrenia risk gene neuregulin-1.
Prog Neuropsychopharmacol Biol Psychiatry. 2008;32(2):462-6.     PMID: 17980471      (Feb 2008)

Morris DW, Murphy K, Kenny N, Purcell SM, McGhee KA, Schwaiger S, Nangle JM, Donohoe G, Clarke S, Scully P, Quinn J, Meagher D, Baldwin P, Crumlish N, O'Callaghan E, Waddington JL, Gill M, Corvin AP. .
Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility.
Biol Psychiatry. 2008;63(1):24-31.     PMID: 17618940      (Jan 2008)

Babovic D, O'Tuathaigh CM, O'Sullivan GJ, Clifford JJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL. .
Exploratory and habituation phenotype of heterozygous and homozygous COMT knockout mice.
Behav Brain Res. 2007;183:236-9.     PMID: 17707921      (Nov 2007)

Corvin A, McGhee KA, Murphy K, Donohoe G, Nangle JM, Schwaiger S, Kenny N, Clarke S, Meagher D, Quinn J, Scully P, Baldwin P, Browne D, Walsh C, Waddington JL, Morris DW, Gill M. .
Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample.
Am J Med Genet B Neuropsychiatr Genet. 2007;144B(7):949-53.     PMID: 17492767      (Oct 2007)

Teper Y, Whyte D, Cahir E, Lester HA, Grady SR, Marks MJ, Cohen BN, Fonck C, McClure-Begley T, McIntosh JM, Labarca C, Lawrence A, Chen F, Gantois I, Davies PJ, Petrou S, Murphy M, Waddington J, Horne MK, Berkovic SF, Drago J. .
Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation.
J Neurosci. 2007;27(38):10128-42.     PMID: 17881519      (Sep 2007)

Aono Y, Saigusa T, Watanabe S, Iwakami T, Mizoguchi N, Ikeda H, Ishige K, Tomiyama K, Oi Y, Ueda K, Rausch WD, Waddington JL, Ito Y, Koshikawa N, Cools AR. .
Role of alpha adrenoceptors in the nucleus accumbens in the control of accumbal noradrenaline efflux: a microdialysis study with freely moving rats.
J Neural Transm. 2007;114(9):1135-42.     PMID: 17533511      (Sep 2007)

Waddington JL, Corvin AP, Donohoe G, O'Tuathaigh CM, Mitchell KJ, Gill M. .
Functional genomics and schizophrenia: endophenotypes and mutant models.
Psychiatr Clin North Am. 2007;30(3):365-99. Review.     PMID: 17720028      (Sep 2007)

Waddington JL. .
Neuroimaging and other neurobiological indices in schizophrenia: relationship to measurement of functional outcome.
Br J Psychiatry Suppl. 2007;50:s52-7. Review.     PMID: 18019045      (Aug 2007)

O'Tuathaigh CM, Babovic D, O'Sullivan GJ, Clifford JJ, Tighe O, Croke DT, Harvey R, Waddington JL. .
Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1.
Neuroscience. 2007;147(1):18-27.     PMID: 17512671      (Jun 2007)

Ishige K, Takagi N, Imai T, Rausch WD, Kosuge Y, Kihara T, Kusama-Eguchi K, Ikeda H, Cools AR, Waddington JL, Koshikawa N, Ito Y. .
Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods.
J Pharmacol Sci. 2007;104(1):46-55.     PMID: 17452809      (May 2007)

Hennessy RJ, Baldwin PA, Browne DJ, Kinsella A, Waddington JL. .
Three-dimensional laser surface imaging and geometric morphometrics resolve frontonasal dysmorphology in schizophrenia.
Biol Psychiatry. 2007;61(10):1187-94.     PMID: 17217929      (May 2007)

Gantois I, Fang K, Jiang L, Babovic D, Lawrence AJ, Ferreri V, Teper Y, Jupp B, Ziebell J, Morganti-Kossmann CM, O'Brien TJ, Nally R, Schutz G, Waddington J, Egan GF, Drago J. .
Ablation of D1 dopamine receptor-expressing cells generates mice with seizures, dystonia, hyperactivity, and impaired oral behavior.
Proc Natl Acad Sci U S A. 2007;104(10):4182-7.     PMID: 17360497      (Mar 2007)

Makihara Y, Okuda Y, Kawada C, Matsumoto M, Waddington JL, Koshikawa N, Tomiyama K. .
Differential involvement of cyclase- versus non-cyclase-coupled D1-like dopamine receptors in orofacial movement topography in mice: studies with SKF 83822.
Neurosci Lett. 2007;415(1):6-10.     PMID: 17234342      (Mar 2007)

O'Tuathaigh CM, Babovic D, O'Meara G, Clifford JJ, Croke DT, Waddington JL. .
Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour.
Neurosci Biobehav Rev. 2007;31(1):60-78.     PMID: 16782199      (Jan 2007)

Clarke M, Whitty P, Browne S, Mc Tigue O, Kinsella A, Waddington JL, Larkin C, O'Callaghan E .
Suicidality in first episode psychosis.
Schizophr Res. 2006;86(1-3):221-5.     PMID: 16846719      (Sep 2006)

Clarke M, Whitty P, Browne S, McTigue O, Kamali M, Gervin M, Kinsella A, Waddington JL, Larkin C, O'Callaghan E .
Untreated illness and outcome of psychosis.
Br J Psychiatry. 2006;189:235-40.     PMID: 16946358      (Sep 2006)

Tomiyama K, Makihara Y, Yamamoto H, O'Sullivan G, Nally RE, Tighe O, Kinsella A, Fienberg AA, Grandy DK, Sibley DR, Croke DT, Koshikawa N, Waddington JL. .
Disruption of orofacial movement topographies in congenic mutants with dopamine D5 but not D4 receptor or DARPP-32 transduction 'knockout'.
Eur Neuropsychopharmacol. 2006;16(6):437-45     PMID: 16413758      (Aug 2006)

Fujita S, Lee J, Kiguchi M, Uchida T, Cools AR, Waddington JL, Koshikawa N. .
Topographical resolution of jaw movements mediated by cyclase- vs. non-cyclase-coupled dopamine D(1)-like receptors: studies with SK&F 83822.
Eur J Pharmacol. 2006;538(1-3):94-100.     PMID: 16682023      (May 2006)

O'Sullivan GJ, Kinsella A, Grandy DK, Tighe O, Croke DT, Waddington JL. .
Ethological resolution of behavioral topography and D2-like vs. D1-like agonist responses in congenic D4 dopamine receptor "knockouts": identification of D4:D1-like interactions.
Synapse. 2006;59(2):107-18.     PMID: 16320306      (Feb 2006)

Norton N, Moskvina V, Morris DW, Bray NJ, Zammit S, Williams NM, Williams HJ, Preece AC, Dwyer S, Wilkinson JC, Spurlock G, Kirov G, Buckland P, Waddington JL, Gill M, Corvin AP, Owen MJ, O'Donovan MC. .
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.
Am J Med Genet B Neuropsychiatr Genet. 2006;141B(1):96-101.     PMID: 16249994      (Jan 2006)

Hennessy RJ, McLearie S, Kinsella A, Waddington JL. .
Facial shape and asymmetry by three-dimensional laser surface scanning covary with cognition in a sexually dimorphic manner.
J Neuropsychiatry Clin Neurosci. 2006;18(1):73-80.     PMID: 16525073      (Jan 2006)

O'Tuathaigh CM, O'Sullivan GJ, Kinsella A, Harvey RP, Tighe O, Croke DT, Waddington JL. .
Sexually dimorphic changes in the exploratory and habituation profiles of heterozygous neuregulin-1 knockout mice.
Neuroreport. 2006;17(1):79-83     PMID: 16361955      (Jan 2006)

Parish CL, Nunan J, Finkelstein DI, McNamara FN, Wong JY, Waddington JL, Brown RM, Lawrence AJ, Horne MK, Drago J. .
Mice lacking the alpha4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and possess impaired dopamine transporter function.
Mol Pharmacol. 2005 Nov;68(5):1376-86.     PMID: 16077034      (Nov 2005)

Parish CL, Nunan J, Finkelstein DI, McNamara FN, Wong JY, Waddington JL, Brown RM, Lawrence AJ, Horne MK, Drago J. .
Mice lacking the alpha4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and possess impaired dopamine transporter function.
Mol Pharmacol. 2005 Nov;68(5):1376-86.     PMID: 16077034      (Nov 2005)

Waddington JL, O'Tuathaigh C, O'Sullivan G, Tomiyama K, Koshikawa N, Croke DT. .
Phenotypic studies on dopamine receptor subtype and associated signal transduction mutants: insights and challenges from 10 years at the psychopharmacology-molecular biology interface.
Psychopharmacology (Berl). 2005 Oct;181(4):611-38.     PMID: 16041535      (Oct 2005)

Hennessy RJ, McLearie S, Kinsella A, Waddington JL. .
Facial surface analysis by 3D laser scanning and geometric morphometrics in relation to sexual dimorphism in cerebral--craniofacial morphogenesis and cognitive function.
J Anat. 2005 Sep;207(3):283-95.     PMID: 16185253      (Sep 2005)

McGhee KA, Morris DW, Schwaiger S, Nangle JM, Donohoe G, Clarke S, Meagher D, Quinn J, Scully P, Waddington JL, Gill M, Corvin A. .
Investigation of the apolipoprotein-L (APOL) gene family and schizophrenia using a novel DNA pooling strategy for public database SNPs.
Schizophr Res. 2005 Jul;76(2-3):231-8.     PMID: 15949655      (Jul 2005)

Baldwin P, Browne D, Scully PJ, Quinn JF, Morgan MG, Kinsella A, Owens JM, Russell V, O'Callaghan E, Waddington JL. .
Epidemiology of first-episode psychosis: illustrating the challenges across diagnostic boundaries through the Cavan-Monaghan study at 8 years.
Schizophr Bull. 2005 Jul;31(3):624-38.     PMID: 15944446      (Jul 2005)

O'Sullivan GJ, Kinsella A, Sibley DR, Tighe O, Croke DT, Waddington JL. .
Ethological resolution of behavioural topography and D1-like versus D2-like agonist responses in congenic D5 dopamine receptor mutants: identification of D5:D2-like interactions.
Synapse. 2005 Mar 15;55(4):201-11.     PMID: 15668951      (Mar 2005)

Makihara Y, Yamamoto H, Inoue M, Tomiyama K, Koshikawa N, Waddington JL. .
Topographical effects of D1-like dopamine receptor agonists on orofacial movements in mice and their differential regulation via oppositional versus synergistic D1-like: D2-like interactions: cautionary observations on SK&F 82958 as an anomalous agent.
J Psychopharmacol. 2004 Dec;18(4):484-95.     PMID: 15585467      (Dec 2004)

Nally RE, Kinsella A, Tighe O, Croke DT, Fienberg AA, Greengard P, Waddington JL. .
Ethologically based resolution of D2-like dopamine receptor agonist-versus antagonist-induced behavioral topography in dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein of 32 kDa "knockout" mutants congenic on the C57BL/6 genetic background.
J Pharmacol Exp Ther. 2004 Sep;310(3):1281-7.     PMID: 15140917      (Sep 2004)

O'Sullivan GJ, Clifford JJ, Tomiyama K, Koshikawa N, Drago J, Sibley DR, Croke DT, Waddington JL. .
D1-like dopamine receptor-mediated function in congenic mutants with D1 vs. D5 receptor "knockout".
J Recept Signal Transduct Res. 2004 Aug;24(3):107-16.     PMID: 15521357      (Aug 2004)

Meagher DJ, Quinn JF, Bourke S, Linehan S, Murphy P, Kinsella A, Mullaney J, Waddington JL. .
Longitudinal assessment of psychopathological domains over late-stage schizophrenia in relation to duration of initially untreated psychosis: 3-year prospective study in a long-term inpatient population.
Psychiatry Res. 2004 May 30;126(3):217-27.     PMID: 15157748      (May 2004)

Williams NM, Preece A, Morris DW, Spurlock G, Bray NJ, Stephens M, Norton N, Williams H, Clement M, Dwyer S, Curran C, Wilkinson J, Moskvina V, Waddington JL, Gill M, Corvin AP, Zammit S, Kirov G, Owen MJ, O'Donovan MC. .
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).
Arch Gen Psychiatry. 2004 Apr;61(4):336-44.     PMID: 15066891      (Apr 2004)

Hennessy RJ, Lane A, Kinsella A, Larkin C, O'Callaghan E, Waddington JL. .
3D morphometrics of craniofacial dysmorphology reveals sex-specific asymmetries in schizophrenia.
Schizophr Res. 2004 Apr 1;67(2-3):261-8.     PMID: 14984886      (Apr 2004)

Scully PJ, Owens JM, Kinsella A, Waddington JL. .
Schizophrenia, schizoaffective and bipolar disorder within an epidemiologically complete, homogeneous population in rural Ireland: small area variation in rate.
Schizophr Res. 2004 Apr 1;67(2-3):143-55.     PMID: 14984873      (Apr 2004)

O'Sullivan GJ, Roth BL, Kinsella A, Waddington JL. .
SK&F 83822 distinguishes adenylyl cyclase from phospholipase C-coupled dopamine D1-like receptors: behavioural topography.
Eur J Pharmacol. 2004 Feb 23;486(3):273-80.     PMID: 14985049      (Feb 2004)

Waddington JL, Scully PJ, Quinn JF, Meagher DJ, Morgan MG .
The origin and course of schizophrenia: implications for clinical practice.
J Psychiatr Pract. 2001 Jul;7(4):247-52.     PMID: 15990531      (Jul 2001)